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招贤纳士
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本课题组招收具有以下研究背景的博士后：

1. 细胞生物学

2. 分子生物学

3. 转基因鼠相关研究

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联系人：骞老师

电　话：029-88461840

邮　箱：

qianair@nwpu.edu.cn

通讯地址：陕西省西安市友谊西路127号，710072

研究成果

一、论文(*: 通讯作者)                                       

（一）2023-2024年

  1. Huai Y, Wang X, Mao W, Wang X, Zhao Y, Chu X,Huang Q, Ru K, Zhang L, Li Y, Chen Z, Qian A*. HuR-positive stress granules:Potential targets for age-related osteoporosis. Aging Cell. 2024Mar;23(3):e14053. doi: 10.1111/acel.14053. Epub 2024 Feb 20. PMID: 38375951;PMCID: PMC10928564.

  2. Dang K, Gao Y, Wang H, Yang H, Kong Y, Jiang S,Qian A*. Integrated metabolomics and proteomics analysis to understand muscleatrophy resistance in hibernating Spermophilus dauricus. Cryobiology. 2024Mar;114:104838. doi: 10.1016/j.cryobiol.2023.104838. Epub 2023 Dec 12. PMID:38097057.

  3. Huai Y, Wang X, Mao W, Wang X, Zhao Y, Chu X,Huang Q, Ru K, Zhang L, Li Y, Chen Z, Qian A*. HuR-positive stress granules:Potential targets for age-related osteoporosis. Aging Cell. 2024Mar;23(3):e14053. doi: 10.1111/acel.14053. Epub 2024 Feb 20. PMID: 38375951;PMCID: PMC10928564.

（二）2022-2023年

  1. Wu Z#, Hu L#, Ru K, Zhang W, Xu X, Liu S, Liu H, Jia Y, Liang S, Chen Z, Qian A*. Ellagic acid inhibits CDK12 to increase osteoblast differentiation and alleviate osteoporosis in hindlimb-unloaded and ovariectomized mice. Phytomedicine. 2023 Jun;114:154745. doi: 10.1016/j.phymed.2023.154745. Epub 2023 Mar 6. PMID: 36931096.

  2. Pei J#, Tian Y#, Ye W#, Han J#, Dang Y, Cheng T, Wang W, Zhao Y, Ye W, Huangfu S, Li Y*, Zhang F*, Lei Y*, Qian A*. A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection. Cell Biosci. 2023 Sep 12;13(1):167 (中科院2区, IF: 7.5)

  3. Gao S, Yang W, Xu M, Zhang H, Yu H, Qian A*, Zhang W*. U-MLP: MLP-based ultralight refinement network for medical image segmentation. Comput Biol Med. 2023 Sep 9;165:107460. doi: 10.1016/j.compbiomed.2023.107460.

  4. Zhang K, Qiu W, Li H, Li J, Wang P, Chen Z, Lin X, Qian A*. MACF1 overexpression in BMSCs alleviates senile osteoporosis in mice through TCF4/miR-335-5p signaling pathway. J Orthop Translat. 2023 Mar 15;39:177-190. doi: 10.1016/j.jot.2023.02.003. PMID: 36969134; PMCID: PMC10036500.

  5. Qiu W#, Lin X#, Yang S, Chen Z, Zhang K, Yang C, Li Y, Miao Z, Deng X, Duan X*, Qian A*. MACF1 deficiencysuppresses tooth mineralization through IGF1 mediated crosstalk betweenodontoblasts and ameloblasts, Genes & Diseases. 2023.

  6. Han J, Na R, Zhao N, Yuan X, Fu L, Jing J, Qian A*, Ye W. Macrophage-Targeted Dextran Sulfate-Dexamethasone Conjugate Micelles for Effective Treatment of Rheumatoid Arthritis[J]. Molecules, 2023, 28(2): 591.

  7. Yang C, Tian Y, Zhao F, Qian H, Liu Z, He C, Li H, Li Y, Miao Z, Qian A*. Microtubule actin crosslinking factor 1 functions as a novel therapeutic target in lung metastasis of osteosarcoma[J]. Genes & Diseases, 2023, 10(2): 325.

  8. Zhao Y, Deng X, Tan S, Zhang J, Han J, Wang X, Pei J, Li H, Deng X, Yin C, Yin D, Tian Y, Qian A*. Co-Polymer Carrier with Dual Advantages of Cartilage-Penetrating and Targeting Improves Delivery and Efficacy of MicroRNA Treatment of Osteoarthritis. Adv Healthc Mater. 2023 Jan;12(6):e2202143. doi: 10.1002/adhm.202202143. Epub 2022 Dec 25. PMID: 36511367.

  9. Cao T, Lu Y, Wang Q, Qin H, Li H,Guo H, Ge M, Glass S E, Singh B, Zhang W, Dong J, Du F, Qian A, Tian Y,Wang X, Li C, Wu K, Fan D, Nie Y, Coffey R J, Zhao X. A CGA/EGFR/GATA2 positivefeedback circuit confers chemoresistance in gastric cancer. The Journal ofclinical investigation. 2022, 132, (6), e154074.

  10. Dang K, Jiang S, Gao Y, Qian A*.The role of protein glycosylation in muscle diseases. Molecular biologyreports. 2022.

  11. Su P, Tian Y, Yin C, Wang X, Li D,Yang C, Pei J, Deng X, King S, Li Y, QianA*. MACF1 promotes osteoblastic cell migration by regulating MAP1B throughthe GSK3beta/TCF7 pathway. Bone. 2022, 154, 116238.

  12. Tian Y, Zhao Y, Yin C, Tan S, WangX, Yang C, Zhang T D, Zhang X, Ye F, Xu J, Wu X, Ding L, Zhang J, Pei J, Wang XT, Zhang R X, Xu J, Wang W, Filipe C D M, Hoare T, Yin D C*, Qian A*, Deng X*. Polyvinylamine withmoderate binding affinity as a highly effective vehicle for RNA delivery.Journal of controlled release: official journal of the Controlled ReleaseSociety. 2022, 345, 20-37.

  13. Wang X, Tian Y, Liang X, Yin C, HuaiY, Zhao Y, Huang Q, Chu X, Wang W, QianA*. Bergamottin promotes osteoblast differentiation and bone formation viaactivating the Wnt/β-catenin signaling pathway. Food & function. 2022, 13,(5), 2913-2924.

  14. Yin C, Tian Y, Li D, Yu Y, Jiang S,Hou Y, Deng M, Zheng K, Zhang Y, Deng X, Chen Z, Miao Z, Hao Q, Li Y, Qian A*. Long noncoding RNA Lnc-DIFinhibits bone formation by sequestering miR-489-3p. iScience. 2022, 25, (3),103949.

  15. Yang C, Tian Y, Zhao F, Huang Q, LiuZ, He C, Li H, Li Y, Mao Z, Qian A*.Microtubule actin crosslinking factor 1 functions as a novel therapeutic targetin lung metastasis of osteosarcoma. Genes & Diseases. 2022.

  16. Lin X, Xiao Y, Zhang K, Yang D, MiaoZ, Deng X, Chen Z, Qian A*.Knockdown of Macf1 Inhibits the Migration and Cytoskeletal Arrangement ofPre-Osteoclasts Induced by Simulated Microgravity[J]. Acta Astronautica, 2022,190, 149-159.

  17. Chen Z, Huai Y, Chen G, Liu S, Zhang Y, Li D, Zhao F, Chen X, Mao W, Wang X, Yin C, Yang C, Xu X, Ru K, Deng X, Hu L, Li Y, Peng S, Zhang G, Lin X, Qian A*. MiR-138-5p Targets MACF1 to Aggravate Aging-related Bone Loss. Int J Biol Sci. 2022 Jul 18;18(13):4837-4852. doi: 10.7150/ijbs.71411. PMID: 35982896; PMCID: PMC9379396.（生物学SCI 2区）（IF: 7.666）

  18. Huai Y, Mao W, Wang X, Lin X, Li Y, Chen Z, Qian A*. How do RNA binding proteins trigger liquid-liquid phase separation in human health and diseases? Biosci Trends. 2022 Dec 26;16(6):389-404. doi: 10.5582/bst.2022.01449. Epub 2022 Dec 3. PMID: 36464283.（生物学JCR Q1，IF: 9.083）

  19. Patil S, Hu L, Zhu C, Xian CJ, Qian A*. Editorial: Development, metabolism, senescence and mechanotransduction of bone. Front Cell Dev Biol. 2022 Dec 8;10:1103581. doi: 10.3389/fcell.2022.1103581. PMID: 36568978; PMCID: PMC9773981.

  20. Zhao, X., S. Patil, A. Qian* and C. Zhao. Bioactive compounds of Polygonatum sibiricum-Therapeutic effect and biological activity[J]. Endocrine, Metabolic & Immune Disorders-Drug Targets (Formerly Current Drug Targets-Immune, Endocrine & Metabolic Disorders), 2022, 22(1): 26-37.

  21. Huai Y, Chen Z, Deng X, Wang X, Mao W, Miao Z, Li Y, Li H, Lin X, Qian A*. An integrated genome-wide analysis identifies HUR/ELAVL1 as a positive regulator of osteogenesis through enhancing the β-catenin signaling activity. Genes Dis. 2022 May 13;10(2):377-380. doi: 10.1016/j.gendis.2022.04.022. PMID: 37223513; PMCID: PMC10201595.（遗传学SCI 1区top）（IF: 7.376）

  22. Dang K, Farooq HMU, Dong J, Yang H, Kong Y, Wang H, Jiang S, Gao Y, Qian A*. Transcriptomic and proteomic time-course analyses based on Metascape reveal mechanisms against muscle atrophy in hibernating Spermophilus dauricus. Comp Biochem Physiol A Mol Integr Physiol. 2023 Jan;275:111336. doi: 10.1016/j.cbpa.2022.111336. Epub 2022 Oct 22. PMID: 36280225.

（三）2021年

  1. Bai D, Feng H, Yang J, Yin A, Lin X,Qian A, Sugiyama H. Genomic analysisuncovers prognostic and immunogenic characteristics of ferroptosis for clearcell renal cell carcinoma. Molecular therapy. Nucleic acids. 2021, 25, 186-197.

  2. Bai D, Feng H, Yang J, Yin A, Qian A, Sugiyama H. Landscape of immunecell infiltration in clear cell renal cell carcinoma to aid immunotherapy.Cancer Sci. 2021, 112, (6), 2126-2139.

  3. Feng R, Patil S, Zhao X, Miao Z, Qian A*. RNA Therapeutics - Researchand Clinical Advancements. Frontiers in molecular biosciences. 2021, 8, 710738.

  4. Hu L, Yin C, Chen D, Wu Z, Liang S,Zhang Y, Huang Z, Liu S, Xu X, Chen Z, Zhang Y, Qian A*. MACF1 promotes osteoblast differentiation by sequesteringrepressors in cytoplasm. Cell death and differentiation. 2021, 28, (7),2160-2178.

  5. Li D, Liu J, Yang C, Tian Y, Yin C,Hu L, Chen Z, Zhao F, Zhang R, Lu A, Zhang G*, Qian A*. Targeting long noncoding RNA PMIF facilitatesosteoprogenitor cells migrating to bone formation surface to promote boneformation during aging. Theranostics. 2021, 11, (11), 5585-5604.

  6. Ma X, Tian Y, Xue K, Huai Y, PatilS, Deng X, Hao Q, Li D, Miao Z, Zhang W, QianA*. Kaempferide enhances antioxidant capacity to promote osteogenesisthrough FoxO1/β-catenin signaling pathway. European journal of pharmacology.2021, 911, 174555.

  7. Wang H, Liu J, Kong Q, Li L, Gao J,Fang L, Liu Z, Fan X, Li C, Lu Q, Qian A*.Cytotoxicity and inflammatory effects in human bronchial epithelial cellsinduced by polycyclic aromatic hydrocarbons mixture. Journal of appliedtoxicology : JAT. 2021, 41, (11), 1803-1815.

  8. Wang H, Zhang W, Liu J, Gao J, FangL E, Liu Z, Xia B, Fan X, Li C, Lu Q, QianA*. NF-κB and FosB mediate inflammation and oxidative stress in the blastlung injury of rats exposed to shock waves. Acta Biochim Biophys Sin(Shanghai). 2021, 53, (3), 283-293.

  9. Xu X, Liu S, Liu H, Ru K, Jia Y, WuZ, Liang S, Khan Z, Chen Z, Qian A*,Hu L*. Piezo Channels: Awesome Mechanosensitive Structures in CellularMechanotransduction and Their Role in Bone. Int J Mol Sci. 2021, 22, (12),6429.

  10. Yin C, Tian Y, Hu L, Yu Y, Wu Z,Zhang Y, Wang X, Miao Z, Qian A*.MACF1 alleviates aging-related osteoporosis via HES1. J Cell Mol Med. 2021, 25,(13), 6242-6257.

  11. Yin C, Tian Y, Yu Y, Li D, Miao Z,Su P, Zhao Y, Wang X, Pei J, Zhang K, QianA*. Long noncoding RNA AK039312 and AK079370 inhibits bone formation viamiR-199b-5p. Pharmacol Res. 2021, 163, 105230.

  12. Zhao X, Patil S, Xu F, Lin X, Qian A*. Role of Biomolecules inOsteoclasts and Their Therapeutic Potential for Osteoporosis. Biomolecules.2021, 11, (5), 747.

  13. Zhao X, Patil S, Qian A*, Zhao C. Bioactive Compounds ofPolygonatum sibiricum - Therapeutic Effect and Biological Activity. Endocrine,metabolic & immune disorders drug targets. 2021, 22, (1), 26-37.

  14. Chen Z, Zhang Y, Zhao F, Yin C, Qian A. Mir-138–5p Negatively RegulatesOsteoblast Differentiation through Inhibiting Β-Catenin under SimulatedMicrogravity in Mc3t3-E1 Cells[J]. Acta Astronautica, 2021, 182(2002), 240-250.

  15. Huai Y,Zhang W, Wang W, Dang K, Jiang S, Li D, Li M, Hao Q, Miao Z, Li Y*, QianA*. Systems pharmacology dissection of action mechanisms for herbs inosteoporosis treatment. Chinese Herbal Medicines. 2021, 13, (3), 313-331.

（四）2020年

  1. Chen Z, Zhang Y, Zhao F, Yin C, YangC, Wang X, Wu Z, Liang S, Li D, Lin X, Tian Y, Hu L, Li Y, Qian A*. Recombinant Irisin Prevents the Reduction of OsteoblastDifferentiation Induced by Stimulated Microgravity through Increasing β-CateninExpression. Int J Mol Sci. 2020, 21, (4),1259.

  2. Chen Z, Zhao F, Liang C, Hu L, Li D,Zhang Y, Yin C, Chen L, Wang L, Lin X, Su P, Ma J, Yang C, Tian Y, Zhang W, LiY, Peng S, Chen W, Zhang G, Qian A*.Silencing of miR-138-5p sensitizes bone anabolic action to mechanical stimuli.Theranostics. 2020, 10, (26), 12263-12278.

  3. Dang K, Zhang W, Jiang S, Lin X, Qian A*. Application of LectinMicroarrays for Biomarker Discovery. Chemistry Open. 2020, 9, (3), 285-300.

  4. Gao Y, Patil S, Qian A*. The Role of MicroRNAs in Bone Metabolism and Disease. IntJ Mol Sci. 2020, 21, (17), 6081.

  5. Gao Y, Dang K, Zhang W, Liu F, PatilS, Qadir A, Ding A, Qian A*. A 1,8-naphthalimide-[12]aneN(3) derivative forefficient Cu(2+) recognition, lysosome staining and siRNA delivery. Colloidsand surfaces. B, Biointerfaces. 2020, 185, 110607.

  6. Gao Y, Huangfu S, Patil S, Tang Q,Sun W, Li Y, Lu Z, Qian A*. [12]aneN(3)-based multifunctional compounds asfluorescent probes and nucleic acids delivering agents. Drug Deliv. 2020, 27,(1), 66-80.

  7. Huai Y, Zhang W, Chen Z, Zhao F,Wang W, Dang K, Xue K, Gao Y, Jiang S, Miao Z, Li M, Hao Q, Chen C, Qian A*. A Comprehensive Analysis ofMicroRNAs in Human Osteoporosis. Front Endocrinol (Lausanne). 2020, 11, 516213.

  8. Li D, Yang C, Yin C, Zhao F, Chen Z,Tian Y, Dang K, Jiang S, Zhang W, Zhang G, QianA*. LncRNA, Important Player in Bone Development and Disease. Endocrine,metabolic & immune disorders drug targets. 2020, 20, (1), 50-66.

  9. Liang S, Hu L, Wu Z, Chen Z, Liu S,Xu X, Qian A*. CDK12: A PotentTarget and Biomarker for Human Cancer Therapy. Cells. 2020, 9, (6), 1483.

  10. Lin X, Chen Q, Xiao Y, Gao Y, AhmedI, Li M, Li H, Zhang K, Qiu W, Liu X, Boccaccini A R, Qian A*. Phosphate glass fibers facilitate proliferation andosteogenesis through Runx2 transcription in murine osteoblastic cells. Journalof biomedical materials research. Part A. 2020, 108, (2), 316-326.

  11. Lin X, Patil S, Gao Y G, Qian A*. The Bone Extracellular Matrixin Bone Formation and Regeneration. Front Pharmacol. 2020, 11, 757.

  12. Lin X, Zhang K, Wei D, Tian Y, GaoY, Chen Z, Qian A*. The Impact ofSpaceflight and Simulated Microgravity on Cell Adhesion. Int J Mol Sci. 2020,21, (9), 3031.

  13. Liu S, Xu X, Liang S, Chen Z, ZhangY, Qian A*, Hu L*. The Applicationof MSCs-Derived Extracellular Vesicles in Bone Disorders: Novel Cell-FreeTherapeutic Strategy. Front Cell Dev Biol. 2020, 8, 619.

  14. Liu Z, Dang K, Li C, Gao J, Wang H,Gao Y, Zhao B, Fan P, Qian A*.Isolation and identification of a novel bacterium, Pseudomonas sp. ZyL-01,involved in the biodegradation of CL-20. AMB Express. 2020, 10, (1), 196.

  15. Ma J, Lin X, Chen C, Li S, Zhang S,Chen Z, Li D, Zhao F, Yang C, Yin C, Qiu W, Xiao Y, Zhang K, Miao Z, Yang T, Qian A*. Circulating miR-181c-5p andmiR-497-5p Are Potential Biomarkers for Prognosis and Diagnosis ofOsteoporosis. The Journal of clinical endocrinology and metabolism. 2020, 105,(5), dgz300.

  16. Ma X, Su P, Yin C, Lin X, Wang X,Gao Y, Patil S, War A R, Qadir A, Tian Y, QianA*. The Roles of FoxO Transcription Factors in Regulation of Bone CellsFunction. Int J Mol Sci. 2020, 21, (3), 692.

  17. Patil S, Dang K, Zhao X, Gao Y, Qian A*. Role of LncRNAs and CircRNAsin Bone Metabolism and Osteoporosis. Front Genet. 2020, 11, 584118.

  18. Qadir A, Liang S, Wu Z, Chen Z, HuL, Qian A*. Senile Osteoporosis: TheInvolvement of Differentiation and Senescence of Bone Marrow Stromal Cells. IntJ Mol Sci. 2020, 21, (1), 349.

  19. Qiu W, Ma X, Lin X, Zhao F, Li D,Chen Z, Zhang K, Zhang R, Wang P, Xiao Y, Miao Z, Dang K, Wu X, Qian A*. Deficiency of Macf1 in osterixexpressing cells decreases bone formation by Bmp2/Smad/Runx2 pathway. J CellMol Med. 2020, 24, (1), 317-327.

  20. Su P, Yin C, Li D, Yang C, Wang X,Pei J, Tian Y, Qian A*. MACF1promotes preosteoblast migration by mediating focal adhesion turnover throughEB1. Biol Open. 2020, 9, (3), 048173.

  21. Wang H, Zhang W, Gao J, Liu J, LiuZ, Xia B, Fan X, Li C, Qian A*.Global gene expression profiling of blast lung injury of goats exposed to shockwave. Chinese journal of traumatology. 2020, 23, (5), 249-257.

  22. War AR, Dang K, Jiang S, Xiao Z,Miao Z, Yang T, Li Y, Qian A*. Roleof cancer stem cells in the development of giant cell tumor of bone. CancerCell Int. 2020, 20, 135.

  23. Yang C, Tian Y, Zhao F, Chen Z, SuP, Li Y, Qian A*. BoneMicroenvironment and Osteosarcoma Metastasis. Int J Mol Sci. 2020, 21, (19),6985.

  24. Yin C, Tian Y, Yu Y, Yang C, Su P,Zhao Y, Wang X, Zhang K, Pei J, Li D, Chen Z, Zhang Y, Miao Z, Qian A*. miR-129-5p Inhibits BoneFormation Through TCF4. Front Cell Dev Biol. 2020, 8, 600641.

  25. Zhang R, Zhang Z, Huang Y, Qian A*, Tan A*. A single ortholog ofteashirt and tiptop regulates larval pigmentation and adult appendagepatterning in Bombyx mori. Insect Biochem Mol Biol. 2020, 121, 103369.

  26. Zhang W, Dang K, Huai Y, Qian A*. Osteoimmunology: The RegulatoryRoles of T Lymphocytes in Osteoporosis. Front Endocrinol (Lausanne). 2020, 11,465.

  27. Zhang Y, Wang H, Zhu G, Qian A*, Chen W. F2r negativelyregulates osteoclastogenesis through inhibiting the Akt and NFκB signalingpathways. Int J Biol Sci. 2020, 16, (9), 1629-1639.

  28. Zhao F, Ma X, Qiu W, Wang P, ZhangR, Chen Z, Su P, Zhang Y, Li D, Ma J, Yang C, Chen L, Yin C, Tian Y, Hu L, LiY, Zhang G, Wu X, Qian A*.Mesenchymal MACF1 Facilitates SMAD7 Nuclear Translocation to Drive BoneFormation. Cells. 2020, 9, (3), 616.

  29. Zhu H, Podesva P, Liu X, Zhang H,Teply T, Xu Y, Chang H, Qian A, Lei Y, Li Y, Niculescu A, Iliescu C, Neuzil P.IoT PCR for pandemic disease detection and its spread monitoring. Sensors andactuators. B, Chemical. 2020, 303, 127098.

  30. Zhang R, Zhang Z, Ye Y, Huang Y, Qian A*, Tan A*. Proboscipedia and SexCombs Reduced Are Essential for Embryonic Labial Palpus Specification in BombyxMori[J]. Journal of Integrative Agriculture, 2020. 19(6), 1482-1491.

  31. Lin X, Qiu W, Xiao Y, Ma J, Xu F,Zhang K, Gao Y, Chen Q, Li Y, Li H, QianA*. Mir-199b-5p Suppresses Tumor Angiogenesis Mediated by VascularEndothelial Cells in Breast Cancer by Targeting Alk1[J]. Frontiers in Genetics,2020, 1397.

（五）2019年

  1. Gao Y, Liu F, Patil S, Li D J, QadirA, Lin X, Tian Y, Li Y, Qian A R*.1,8-Naphthalimide-Based Multifunctional Compounds as Cu(2+) Probes, LysosomeStaining Agents, and Non-viral Vectors. Frontiers in chemistry. 2019, 7, 616.

  2. Hassanshahi M, Su Y W, Khabbazi S,Fan C M, Chen K M, Wang J F, Qian A,Howe P R, Yan D W, Zhou H D, Xian C J. Flavonoid genistein protects bone marrowsinusoidal blood vessels from damage by methotrexate therapy in rats. J CellPhysiol. 2019, 234, (7), 11276-11286.

  3. Li D, Tian Y, Yin C, Huai Y, Zhao Y,Su P, Wang X, Pei J, Zhang K, Yang C, Dang K, Jiang S, Miao Z, Li M, Hao Q,Zhang G, Qian A*. Silencing oflncRNA AK045490 Promotes Osteoblast Differentiation and Bone Formation viaβ-Catenin/TCF1/Runx2 Signaling Axis. Int J Mol Sci. 2019, 20, (24), 6229.

  4. Lin X, Qiu W, Xiao Y, Ma J, Xu F,Zhang K, Gao Y, Chen Q, Li Y, Li H, QianA*. MiR-199b-5p Suppresses Tumor Angiogenesis Mediated by VascularEndothelial Cells in Breast Cancer by Targeting ALK1. Front Genet. 2019, 10,1397.

  5. Lin X, Xiao Y, Chen Z, Ma J, Qiu W,Zhang K, Xu F, Dang K, Qian A*.Microtubule actin crosslinking factor 1 (MACF1) knockdown inhibitsRANKL-induced osteoclastogenesis via Akt/GSK3β/NFATc1 signalling pathway. MolCell Endocrinol. 2019, 494, 110494.

  6. Patil S, Gao Y, Lin X, Li Y, Dang K,Tian Y, Zhang W, Jiang S, Qadir A, QianA*. The Development of Functional Non-Viral Vectors for Gene Delivery. IntJ Mol Sci. 2019, 20, (21), 5491.

  7. Qadir A, Gao Y, Suryaji P, Tian Y,Lin X, Dang K, Jiang S, Li Y, Miao Z, QianA*. Non-Viral Delivery System and Targeted Bone Disease Therapy. Int J MolSci. 2019, 20, (3), 565.

  8. Wang L, Chen W, Guo H, Qian A. Response of membrane tension togravity in an approximate cell model. Theoretical biology & medicalmodelling. 2019, 16, (1), 19.

  9. Yin C, Tian Y, Yu Y, Wang H, Wu Z,Huang Z, Zhang Y, Li D, Yang C, Wang X, Li Y, Qian A*. A novel long noncoding RNA AK016739 inhibits osteoblastdifferentiation and bone formation. J Cell Physiol. 2019, 234, (7),11524-11536.

  10. Zhang W, Huai Y, Miao Z, Chen C,Shahen M, Rahman S U, Alagawany M, El-Hack M E A, Zhao H, Qian A*. Systems pharmacology approach to investigate the molecularmechanisms of herb Rhodiola rosea L. radix. Drug Dev Ind Pharm. 2019, 45, (3),456-464.

  11. Zhang W, Huai Y, Miao Z, Qian A, Wang Y. Systems Pharmacologyfor Investigation of the Mechanisms of Action of Traditional Chinese Medicinein Drug Discovery. Front Pharmacol. 2019, 10, 743.

  12. Zhang W, Huai Y, Wang W, Xue K, ChenL, Chen C, Qian A*. A Retrospectivecohort study on the risk factors of deep vein thrombosis (DVT) for patientswith traumatic fracture at Honghui Hospital. BMJ Open. 2019, 9, (3), e024247.

  13. Zhang W, Xue K, Gao Y, Huai Y, WangW, Miao Z, Dang K, Jiang S, Qian A*.Systems pharmacology dissection of action mechanisms of Dipsaci Radix for osteoporosis.Life Sci. 2019, 235, 116820.

  14. Dang K, Gao Y, Qian A, Dong J. Advances in the Treatment of Colorectal CancerUsing Microrna. in 2019 16th International Bhurban Conference on AppliedSciences and Technology (IBCAST). 2019. IEEE.

  15. Li D, Yang C, Chen Z, Zhao F, Qian A, Liu J, Liang C, Guan D, Ni S,Ren Q. Targeting a Newly Identified Lncrna and Its Interaction with Hur toPromote Osteogenic Cells Migration to Bone Formation Surface for ReversingEstablished Age-Related Osteoporosis. Bone & Mineral Research. 2019, 111.

  16. Wu Z, Liang S, Kuai W, Hu L, Qian A*. Micrornas and Long NoncodingRnas: New Regulators in Cell Fate Determination of Mesenchymal Stem Cells[J].RSC Advances, 2019, 9(64), 37300-37311.

（六）2018年

  1. Gao Y, Alam U, Ding A, Tang Q, TanZ, Shi Y, Lu Z, Qian A*.[12]aneN(3)-based lipid with naphthalimide moiety for enhanced genetransfection efficiency. Bioorganic chemistry. 2018, 79, 334-340.

  2. Gao Y, Lin X, Dang K, Jiang S, TianY, Liu F, Li D, Li Y, Miao Z, Qian A*.Structure-activity relationship of novel low-generation dendrimers for genedelivery. Organic & Biomolecular Chemistry. 2018, 16, (42), 7833-7842.

  3. Hu L, Huang Z, Wu Z, Ali A, Qian A*. Mammalian Plakins, GiantCytolinkers: Versatile Biological Functions and Roles in Cancer. Int J Mol Sci.2018, 19,(4): 974.

  4. Hu L, Su P, Yin C, Zhang Y, Li R,Yan K, Chen Z, Li D, Zhang G, Wang L, Miao Z, Qian A*, Xian C J. Microtubule actin crosslinking factor 1 promotesosteoblast differentiation by promoting β-catenin/TCF1/Runx2 signaling axis. JCell Physiol. 2018, 233, (2), 1574-1584.

  5. Hu L, Yin C, Zhao F, Ali A, Ma J, Qian A*. Mesenchymal Stem Cells: CellFate Decision to Osteoblast or Adipocyte and Application in OsteoporosisTreatment. Int J Mol Sci. 2018, 19, (2), 360.

  6. Li S, Miao Z, Tian Y, Wang H, WangS, He T, Yang Y, Wang P, Ma M, Yang T, Chen T, Liu Z, Gao J, Chen C, Qian A*. Limethason reduces airwayinflammation in a murine model of ovalbumin-induced chronic asthma withoutcausing side effects. Exp Ther Med. 2018, 15, (3), 2269-2276.

  7. Su P, Tian Y, Yang C, Ma X, Wang X,Pei J, Qian A*. Mesenchymal StemCell Migration during Bone Formation and Bone Diseases Therapy. Int J Mol Sci.2018, 19, (8), 2343.

  8. Yin C, Zhang Y, Hu L, Tian Y, ChenZ, Li D, Zhao F, Su P, Ma X, Zhang G, Miao Z, Wang L, Qian A*, Xian C J. Mechanical unloading reduces microtubule actincrosslinking factor 1 expression to inhibit β-catenin signaling and osteoblastproliferation. J Cell Physiol. 2018, 233, (7), 5405-5419.

  9. Zhang Y, Yin C, Hu L, Chen Z, ZhaoF, Li D, Ma J, Ma X, Su P, Qiu W, Yang C, Wang P, Li S, Zhang G, Wang L, Qian A*, Xian C J. MACF1 Overexpressionby Transfecting the 21 kbp Large Plasmid PEGFP-C1A-ACF7 Promotes OsteoblastDifferentiation and Bone Formation. Hum Gene Ther. 2018, 29, (2), 259-270.

（六）2017年及以前

  1. Tian Y, Ma X, Yang C, Su P, Yin C, Qian A*. The Impact of Oxidative Stresson the Bone System in Response to the Space Special Environment. Int J Mol Sci.2017, 18, (10), 2132.

  2. Sun Y, Li D, Zhang R, Peng S, ZhangG, Yang T, Qian A*. Strategies toidentify natural antisense transcripts. Biochimie. 2017, 132, 131-151.

  3. Qian A, Hu L. Spectraplakins, versatile roles in physiology andpathology. Seminars in cell & developmental biology. 2017, 69, 1-2.

  4. Miao Z, Ali A, Hu L, Zhao F, Yin C,Chen C, Yang T, Qian A*. Microtubuleactin cross-linking factor 1, a novel potential target in cancer. Cancer Sci.2017, 108, (10), 1953-1958.

  5. Hu L, Xiao Y, Xiong Z, Zhao F, YinC, Zhang Y, Su P, Li D, Chen Z, Ma X, Zhang G, Qian A*. MACF1, versatility in tissue-specific function and inhuman disease. Seminars in cell & developmental biology. 2017, 69, 3-8.

  6. Chen Z, Zhang Y, Liang C, Chen L,Zhang G, Qian A*. MechanosensitivemiRNAs and Bone Formation. Int J Mol Sci. 2017, 18, (8), 1684.

  7. Ali A, Hu L, Zhao F, Qiu W, Wang P,Ma X, Zhang Y, Chen L, Qian A*.BPAG1, a distinctive role in skin and neurological diseases. Seminars in cell& developmental biology. 2017, 69, 34-39.

  8. Yin C, Zhang Y, Hu L, Tian Y, ChenZ, Li D, Zhao F, Ma X, Su P, Zhang G, Miao Z, Wang L, Xian C, Qian A*. Mechanical unloading reducesmicrotubule actin crosslinking factor 1 expression to inhibit β-cateninsignaling and osteoblast proliferation: Mechano-sensitive MACF1 in osteoblasts.Journal of Cellular Physiology. 2017, 233(1).

  9. Miao Z, Qiu W, Ma X, Qian A*. Advances in Research onEffects of Space Microgravity on Bone Metabolism[J]. J Astronaut, 2017, 38,(3), 219-229.

  10. Yan K, Arfat Y, Li D, Zhao F, ChenZ, Yin C, Sun Y, Hu L, Yang T, Qian A*.Structure Prediction: New Insights into Decrypting Long Noncoding RNAs. Int JMol Sci. 2016, 17, (1).

  11. Li D, Liu J, Guo B, Liang C, Dang L,Lu C, He X, Cheung H, Xu L, Lu C, He B, Liu B, Shaikh A, Li F, Wang L, Yang Z,Au D W, Peng S, Zhang Z, Zhang B, Pan X, QianA, Shang P, Xiao L, Jiang B, Wong C, Xu J, Bian Z, Liang Z, Guo D, Zhu H,Tan W, Lu A, Zhang G. Osteoclast-derived exosomal miR-214-3p inhibitsosteoblastic bone formation. Nature communications. 2016, 7, 10872.

  12. Hu L, Su P, Li R, Yin C, Zhang Y,Shang P, Yang T, Qian A*. Isoforms,structures, and functions of versatile spectraplakin MACF1. BMB reports. 2016,49, (1), 37-44.

  13. Chen Z, Zhao F, Qi Y, Hu L, Li D,Yin C, Su P, Zhang Y, Ma J, Qian J, Zhou H, Zou Y, Qian A*. Simulated Microgravity Alters the Expression ofCytoskeleton-and Atp-Binding-Related Genes in Mlo-Y4 Osteocytes[J]. ActaAstronautica. 2016. 129, 186-192.

  14. Wang Y, Chen Z, Yin C, Ma J, Li D,Zhao F, Sun Y, Hu L, Shang P, Qian A*.GeneChip expression profiling reveals the alterations of energy metabolismrelated genes in osteocytes under large gradient high magnetic fields. PloSone. 2015, 10, (1), e0116359.

  15. Sun Y, Chen Z, Chen X, Yin C, Li D,Ma X, Zhao F, Zhang G, Shang P, Qian A*.Diamagnetic levitation promotes osteoclast differentiation from RAW264.7 cells.IEEE transactions on bio-medical engineering. 2015, 62, (3), 900-908.

  16. Sun Y, Chen X, Chen Z, Ma X, Li D,Shang P, Qian A*. Neuropeptide FFattenuates RANKL-induced differentiation of macrophage-like cells intoosteoclast-like cells. Archives of oral biology. 2015, 60, (2), 282-292.

  17. Liu J, Dang L, Li D, Liang C, He X,Wu H, Qian A, Yang Z, Au D W, ChiangM W, Zhang B T, Han Q, Yue K K, Zhang H, Lv C, Pan X, Xu J, Bian Z, Shang P,Tan W, Liang Z, Guo B, Lu A, Zhang G. A delivery system specificallyapproaching bone resorption surfaces to facilitate therapeutic modulation ofmicroRNAs in osteoclasts. Biomaterials. 2015, 52, 148-160.

  18. Liang C, Guo B, Wu H, Shao N, Li D,Liu J, Dang L, Wang C, Li H, Li S, Lau W K, Cao Y, Yang Z, Lu C, He X, Au D W,Pan X, Zhang B, Lu C, Zhang H, Yue K, QianA, Shang P, Xu J, Xiao L, Bian Z, Tan W, Liang Z, He F, Zhang L, Lu A,Zhang G. Aptamer-functionalized lipid nanoparticles targeting osteoblasts as anovel RNA interference-based bone anabolic strategy. Nature medicine. 2015, 21,(3), 288-294.

  19. Hu L, Li J, Qian A, Wang F, Shang P. Mineralization initiation of MC3T3-E1preosteoblast is suppressed under simulated microgravity condition. Cellbiology international. 2015, 39, (4), 364-372.

  20. Hu L, Su P, Li R, Yan K, Chen Z,Shang P, Qian A*. Knockdown ofmicrotubule actin crosslinking factor 1 inhibits cell proliferation in MC3T3-E1osteoblastic cells. BMB reports. 2015, 48, (10), 583-588.

  21. Arfat Y, Xiao W, Ahmad M, Zhao F, LiD J, Sun Y, Hu L, Chen Z, Zhang G, Iftikhar S, Shang P, Yang T, Qian A*. Role of microRNAs inosteoblasts differentiation and bone disorders. Current medicinal chemistry.2015, 22, (6), 748-758.

  22. Sun Y, Chen Z, Li D, Zhao F, Ma X,Shang P, Yang T, Qian A*.Neuropeptide FF inhibits LPS-mediated osteoclast differentiation of RAW264.7cells. Protein and peptide letters. 2014, 22, (3), 270-284.

  23. Jia B, Xie L, Zheng Q, Yang P, ZhangW, Ding C, Qian A, Shang P. Ahypomagnetic field aggravates bone loss induced by hindlimb unloading in ratfemurs. PloS one. 2014, 9, (8), e105604.

  24. Arfat Y, Xiao W, Iftikhar S, Zhao F,Li D, Sun Y, Zhang G, Shang P, Qian A*.Physiological effects of microgravity on bone cells. Calcified tissueinternational. 2014, 94, (6), 569-79.

  25. Arfat Y, Mahmood N, Tahir M U,Rashid M, Anjum S, Zhao F, Li D, Sun Y, Hu L, Chen Z, Yin C, Shang P, Qian A*. Effect of imidacloprid onhepatotoxicity and nephrotoxicity in male albino mice. Toxicology reports.2014, 1, 554-561.

  26. QianA, Gao X, Zhang W, Li J, Wang Y, Di S, Hu L, Shang P.Largegradient high magnetic fields affect osteoblast ultrastructure and function bydisrupting collagen I or fibronectin/αβ1 integrin. PloS one. 2013, 8, (1),e51036.

  27. Liu J, Peng Y, Cui Z, Wu Z, Qian A, Shang P, Qu L, Li Y, Liu J,Long J. Depressed mitochondrial biogenesis and dynamic remodeling in mousetibialis anterior and gastrocnemius induced by 4-week hindlimb unloading. IUBMBlife. 2012, 64, (11), 901-10.

  28. Guo Y, Yin D, Cao H, Shi J, Zhang C,Liu Y, Huang H, Liu Y, Wang Y, Guo W, QianA, Shang P. Evaporation rate of water as a function of a magnetic field andfield gradient. Int J Mol Sci. 2012, 13, (12), 16916-16928.

  29. Di S, Tian Z, Qian A, Li J, Wu J, Wang Z, Zhang D, Yin D, Brandi M L, Shang P.Large gradient high magnetic field affects FLG29.1 cells differentiation toform osteoclast-like cells. International journal of radiation biology. 2012,88, (11), 806-813.

  30. Meng R, Xu H Y, Di S M, Shi D Y, Qian A R, Wang J F, Shang P. Humanmesenchymal stem cells are sensitive to abnormal gravity and exhibit classicapoptotic features. Acta Biochim Biophys Sin (Shanghai). 2011, 43, (2),133-142.

  31. Di S, Tian Z, Qian A, Gao X, Yu D, Brandi M L, Shang P. Selection of suitablereference genes from bone cells in large gradient high magnetic field based onGeNorm algorithm. Electromagnetic biology and medicine. 2011, 30, (4), 261-269.

  32. Li J, Wang Z, He G, Zhang W, Qian A, Shang P. Application ofglutaraldehyde to in-cell Western assay for normalization. Analyticalbiochemistry. 2010, 398, (2), 254-256.

  33. Yang P, Jia B, Ding C, Wang Z, Qian A, Shang P. Whole-body vibrationeffects on bone before and after hind-limb unloading in rats. Aviation, space,and environmental medicine. 2009, 80, (2), 88-93.

  34. Wang Z, Yang P, Xu H, Qian A, Hu L, Shang P. Inhibitoryeffects of a gradient static magnetic field on normal angiogenesis.Bioelectromagnetics. 2009, 30, (6), 446-453.

  35. QianA, Hu L, Gao X, Zhang W, Di S, Tian Z, Yang P, Yin D, Weng Y,Shang P. Large gradient high magnetic field affects the association of MACF1with actin and microtubule cytoskeleton. Bioelectromagnetics. 2009, 30, (7),545-555.

  36. QianA, Di S, Gao X, Zhang W, Tian Z, Li J, Hu L, Yang P, Yin D,Shang P. cDNA microarray reveals the alterations of cytoskeleton-related genesin osteoblast under high magneto-gravitational environment. Acta BiochimBiophys Sin (Shanghai). 2009, 41, (7), 561-577.

  37. Tian Z, Zhou B, Qian A, Xu H, Di S, Zhao Y, Zhang Y, Liu J, Huang Y, Shang P.[Cloning of silkworm 3-hydroxyisobutyrate dehydrogenase gene and its expressionpatterns analysis in simulated weightless environment]. Sheng wu gong cheng xuebao = Chinese journal of biotechnology. 2008, 24, (12), 2041-2048.

  38. QianA, Zhang W, Cao J, Yang P, Gao X, Wang Z, Xu H, Weng Y, ShangP. Downregulation of CD147 expression alters cytoskeleton architecture andinhibits gelatinase production and SAPK pathway in human hepatocellularcarcinoma cells. Journal of experimental & clinical cancer research : CR.2008, 27, (1), 50.

  39. Xu H, Qian A, Shang P, Xu J, Kong L, Bian H, Chen Z. siRNA targetedagainst HAb18G/CD147 inhibits MMP-2 secretion, actin and FAK expression inhepatocellular carcinoma cell line via ERK1/2 pathway. Cancer letters. 2007,247, (2), 336-344.

  40. Chen Z, Mi L, Xu J, Song F, Zhang Q,Zhang Z, Xing J, Bian H, Jiang J, Wang X H, Shang P, Qian A, Zhang S, Li L, Li Y, Feng Q, Yu X, Feng Y, Yang X, Tian R,Wu Z, Leng N, Mo T, Kuang A, Tan T, Li Y, Liang D, Lu W, Miao J, Xu G, Zhang Z,Nan K, Han J, Liu Q, Zhang H, Zhu P. Targeting radioimmunotherapy ofhepatocellular carcinoma with iodine (131I) metuximab injection: clinical phaseI/II trials. International journal of radiation oncology, biology, physics.2006, 65, (2), 435-444.

  41. Chen Z, Mi L, Xu J, Yu J, Wang X,Jiang J, Xing J, Shang P, Qian A, LiY, Shaw P X, Wang J, Duan S, Ding J, Fan C, Zhang Y, Yang Y, Yu X, Feng Q, LiB, Yao X, Zhang Z, Li L, Xue X, Zhu P. Function of HAb18G/CD147 in invasion ofhost cells by severe acute respiratory syndrome coronavirus. The Journal ofinfectious diseases. 2005, 191, (5), 755-760.

  42. Yang Y, Li Y, Wang X, Shang P, WangL, Qian A, Yao X, Chen Z.[Purification of colorectal cancer-associated antigen by immuno-affinitychromatography]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal ofcellular and molecular immunology. 2004, 20, (3), 348-351.

  43. Lou C, Feng Y, Qian A, Li Y, Tang H, Shang P, Chen Z. Establishment andcharacterization of human hepatocellular carcinoma cell line FHCC-98. Worldjournal of gastroenterology. 2004, 10, (10), 1462-1465.

  44. Shang P, Qian A, Yang T, Jia M, Mei Q, Cho C, Zhao W, Chen Z. Experimentalstudy of anti-tumor effects of polysaccharides from Angelica sinensis. Worldjournal of gastroenterology. 2003, 9, (9), 1963-1967.

  45. QianA, Shang P, Li Y, Fan C, Chen D, Wang C, Zhu P, Chen Z.[Study on the affinities of antagonistic peptides with HAb18G/CD147 on thehepatocellular carcinoma cells]. Xi bao yu fen zi mian yi xue za zhi = Chinesejournal of cellular and molecular immunology. 2003, 19, (2), 127-129.

  46. Li Y, Shang P, Qian A, Wang L, Yang Y, Chen Z. Inhibitory effects of antisense RNAof HAb18G/CD147 on invasion of hepatocellular carcinoma cells in vitro. Worldjournal of gastroenterology. 2003, 9, (10), 2174-2177.

  47. Huang B, Shang P, Qian A, Wang X, Shi G, Chen Z.Bio-panning of antagonistic peptides against HAb18G/CD147 and their function ofanti-hepatoma invasion. Chinese journal of oncology. 2003, 25, (2), 111-114.

二、专 著

  1. Noncoding RNAs and Bone. Editor: Qianairong, Tian Ye. Singapore: Springer Singapore; 2021.

  2. AirongQian. Antibody Fusion Protein , see Beifen Shen,Zhinan Chen, Minpei Liu ,Ed in Chief, Recombinant Antibodies, 2005,Scientific Press.

  3. 航天医学效应与防护，主编：骞爱荣，蔺枭，陈志浩；科学出版社，2022, ISBN 978-7-03-072612-4.

三、专 利

申请发明专利：

  1. 骞爱荣，陈志浩，田野，谭慎行，骞婧，韩江帆。一种重组miR-218及其生产方法和应用。申请号：202111062682.5。

  2. 印崇，周静梅，李静佳，廖佳梅，罗荣萍，郭晓兰，田野，骞爱荣。一种长链非编码 RNA 及其在制备治疗骨质疏松药物中的应用。申请号：202111675393.2。

  3. 印崇，侯忆梅，邓萌，郭晓兰，陈志浩。一种核酸药物及其应用。申请号：202111554590.9。

  4. 骞爱荣，陈志浩，田野，谭慎行，骞婧，韩江帆。一种重组miR-218及其生产方法和应用。申请号：202111062682.5。

  5. 骞爱荣，陈志浩，田野，谭慎行，骞婧，韩江帆。一种重组miR-218及其生产方法和在毛发再生中的应用。申请号：202111062682.5。

  6. 骞爱荣，田野，裴佳伟，李郁，陈志浩，杨超飞。一种抗水痘-带状疱疹病毒的重组siRNAs及其生产方法和应用。申请号：202110917269.6。

  7. 骞爱荣，裴佳伟，田野，李郁，陈志浩，杨超飞。一种抗水痘-带状疱疹病毒的siRNAs及其应用。申请号：202110917240.8。

  8. 骞爱荣，赵一浦，田野，邓旭东。软骨靶向肽修饰的两亲性高分子聚合物基因载体及其制备方法和应用。申请号：202110915949.4。

  9. 骞爱荣，田野，谭慎行，杨超飞。一种重组人/鼠si-APOB及其生产方法和应用。申请号：202110902016.1。

  10. 骞爱荣，田野，王雪，王味思，梁学超。佛手柑素在预防或治疗骨质疏松和/或骨丢失中的应用。申请号：202110938981.4。

  11. 骞爱荣，杨超飞，田野，赵帆，王雪，黄倩，裴佳伟，陈志浩，骞婧。一种重组siMACF1及其生产方法和应用。申请号：201911406933.X。

  12. 田野，骞爱荣，王雪，裴佳伟，李腾飞，高玉峰，姜维，印崇，苏佩红，谭慎行。一种治疗骨质疏松的中药提取物组合。申请号：201911381106.X。

  13. 骞爱荣、田野、王雪、蔺枭、裴佳伟、苏佩红、印崇、谭慎行、骞婧、赵欣。一种治疗骨质疏松的组合物。申请号：201910855234.7。

  14. 骞爱荣，田野，李郁，王威，张文娟，于观贞，罗晓庆，赵欣。一种病理诊断方法及装置。申请号：201910513920.6。

  15. 王鸿，高俊宏，骞爱荣，刘进仁，卢青，范小琳，李亮，张文娟，刘志永。一种肺爆震伤动物模型构建方法及其用途。申请号：202110944545.8。

  16. 王鸿，刘进仁，范小琳，卢青，高俊宏，李亮，骞爱荣，张文娟。肺爆震伤的标志物及筛选方法。申请号CN202110989602.4。

  17. 骞爱荣，赵一浦，田野，谭慎行，杨超飞。一种抗骨关节炎的重组miR-140及其生产方法和应用。申请号：202110915950.7。

  18. 骞爱荣，田野，裴佳伟，李郁，姜山峰，一种抗Ⅰ型单纯疱疹病毒的重组siRNAs及其应用，申请号：CN202211604984.5。

授权发明专利：

  1. 高永光，骞爱荣，田野，李郁，党凯，姜山峰，罗晓庆，赵欣，杨超飞，萘酰亚胺修饰的树形高分子转基因载体、其制备方法及应用，专利号：ZL201810641124.6（授权：CN111019961B，授权日期：2022.1.11）

  2. 马小魁,毛东霞,李亭亭,李郁,丁宁,刘陶,黄孢原毛平革菌及其应用。专利号：ZL2016103076961（授权：CN105820963B，授权日期：2019.6.28）

  3. 马小魁，毛东霞，李亭亭，李郁，宋双红，重度石油污染土壤或油泥的序列生物强化处理方法。专利号：ZL2016103085848（授权：CN105921512B，授权日期：2019.5.14）

  4. 梁健，马小魁，郭文英，赵玮玮，陈康健，李郁，周波，李忠煜，王玉珍，佘旭，土曲霉DDT98801及其筛选方法和在降解滴滴涕中的应用。专利号：ZL201810087261X（授权：CN108130281B，授权日期：2019.8.20）

  5. 马小魁,毛东霞,李郁,周波,郭丹丹,马瑶,李亭亭,陈康健,宋双红,一种基于过碳酸钠氧化与微生物强化综合处理重度石油污染土壤或油泥的方法。专利号：ZL2016105409841（授权：CN106077076B，授权日期：2019.6.28）

  6. 马小魁,毛东霞,吴玲玲,李郁,李亭亭,刘陶,枝顶孢霉菌及其应用。专利号：ZL2016103075456（授权：CN105820962B，授权日期：2019.6.25）

  7. 邓旭东，田野，尹大川，骞爱荣，高永光，王雪，李瑞云，张托弟，阳离子聚乙烯胺线形高分子作为转基因载体的应用。专利号：ZL2018110994098（授权：CN109136271B，授权日期：2021.7.20）。

  8. 骞爱荣，王雪，田野，高永光，李瑞云，裴佳伟，杨超飞，苏佩红，赵欣，罗晓庆，一种筛选miRNA调控剂的细胞模型及应用。专利号：ZL 2019105049835（授权：CN110218701B, 日期：2021.7.9）。

  9. 高永光，骞爱荣，田野，李郁，党凯，姜山峰，罗晓庆，赵欣，杨超飞，萘酰亚胺修饰的树形高分子转基因载体、其制备方法及应用[P]。专利号：ZL2018106411246（授权：CN108753830B，授权日期：2021.6.29）。

  10. 骞爱荣，李迪杰，杨超飞，田野，印崇，陈志浩，赵帆，张茹，赵欣，罗晓庆，一种长链非编码RNA lnc-PMIF及其小干扰RNA和应用。专利号：ZL2019112972346（授权：CN110951735B, 授权日期：2021.6.29）。

  11. 高永光、骞爱荣、李郁、田野、党凯、姜山峰、罗晓庆、赵欣，酰胺键联接的萘酰亚胺多功能化合物的合成及应用。专利号：ZL2019103911023（授权： CN110105335B，授权日期：2020.11.24）。

  12. 骞爱荣、高永光、党凯、李郁、田野、姜山峰、罗晓庆、赵欣，酯键联接的萘酰亚胺大环多胺化合物的合成及应用。专利号：ZL2019103911019（授权CN110003210B，授权日期：2020.10.30）。

  13. 骞爱荣，高永光，党凯，田野，张文娟，姜山峰，赵欣，罗晓庆，树枝状分子类阳离子脂质、转基因载体及其制备方法[P]。专利号：ZL2018103599412（授权：CN108395411AB，授权日期：2020.6.30）。

  14. 高永光，骞爱荣，党凯，田野，张文娟，姜山峰，赵欣，罗晓庆，多胺类阳离子脂质、转基因载体及其制备方法[P]。专利号：ZL2018103589887（授权：CN108440426B，授权日期：2019.11.5）。

  15. 骞爱荣; 高永光; 蔺枭; 胡丽芳; 张文娟; 罗晓庆; 赵欣; 李迪杰，骨靶向肽与萘酰亚胺修饰的树形高分子转基因载体、其制备方法及应用。专利号：ZL2018106208270（授权：CN108753829B，授权日期：2021.6.29）。

  16. 骞爱荣，田野，程群燕，喻译锋，罗晓庆，裴佳伟，王雪，杨超飞。一种重组小RNA的生产方法及应用。专利号：ZL201810595579.9（授权：CN108753780B，授权日期：2022.3.29）


四、会 议

  1. Airong Qian*, Zhihao Chen, Yasir Arfat, Lifang Hu, Peng Shang, Ge Zhang. Mechanical unloading sensitive miR-138 targets MACF1 to regulate bone formation. 2015 American Society for Bone and Mineral Research (ASBMR), Seattle, USA, 2015, Oct. 9-12.

  2. Airong Qian*, Lifang Hu, Yulong Sun, Zhihao Chen, Yasir Arfat, Dijie Li, Chong Yin, Peihong Su, Runzhi Li, Kun Yan, Peng Shang, Ge Zhang. The Response of MACF1 to Simulated Microgravity and Its Noncoding RNAs in Regulating Osteogenesis. 6th China-Germany Workshop on Microgravity and Space Life Sciences Hangzhou, China. 2015.Sept.25-28

  3. Airong Qian*, Lifang Hu, Yulong Sun, Zhihao Chen, Yasir Arfat, Dijie Li, Chong Yin, Peihong Su, Runzhi Li, Kun Yan, Peng Shang, Ge Zhang. The role of MACF1 and its noncoding RNA in osteogenesis. The International Chinese Musculoskeletal Research Society (ICMRS) Conference and Xiangya Osteoporosis Forum, Changsha, China. 2015, April 9-11.

  4. AiRong Qian*, Li-Fang Hu, YuLong Sun, DiJie Li, Zhi-Hao Chen, Peng Shang, Ge Zhang. The role of MACF1 inmigration, proliferation and differentiation of Osteoblast and the screening ofthe natural antisense transcripts of MACF1. 2014 American Society for Boneand Mineral Research (ASBMR), Houston, USA. 2014, Sept. 12-15. (ISTP)

  5. AiRong Qian*, LiFang Hu, Yang Wang, Peng Shang. Response and Adaption of Bone Cells to Mechanical Stimulation. 2013 American Society for Bone and Mineral Research (ASBMR),Boltimore, USA. 2013, Oct. 4-7. (ISTP)

  6. AiRong Qian*, Xiang Gao, Wei Zhang, Lifang Hu, Peng Shang, JianPing Jin. Diamagneic levitation changes morphology,cytoskeleton architecture and h2-calponin expression in bone cells. BiophysicalSociety 55th Annual Meeting. Baltimore, Maryland,Mar5-9,2011.

  7. 第十三届全国生物力学学术会议。贵州贵阳，2021年10月5日-9日。2人次。受邀在会议中做了“力学敏感分子MACF1在骨稳态中的作用”汇报，介绍了课题组近期的骨架蛋白MACF1在骨生物力学领域的相关研究成果。陈志浩博士后在青年学者优秀论文分会场做了“miR-138-5p抑制剂作为力学增敏剂可以缓解废用型骨质疏松”的报告，介绍了课题组在废用型骨质疏松的诊断与治疗领域最新突破，该论文被评选为大会优秀学术论文。

  8. 中国细胞生物学学会2021年全国学术大会。重庆，2021年 4月12日-16日。3人次。骞爱荣教授作为分会场“非编码RNA与细胞功能”召集人，组织邀请该分会场报告人，并做了邀请报告。

  9. 2021核酸药物开发论坛，江苏南京，2021年5月7日-8日。骞爱荣做了邀请报告，陈志浩，裴佳伟参会。

  10. 中国细胞生物学学会2021年度“实验室开放日”活动。陕西西安，2021年5月22日。50人次，骞爱荣教授作为会议召集人发起会议。

  11. 第二届分子医学华山论坛暨陕西省创新驱动共同体合成生物新药专委会成立大会，陕西西安，2021年12月11日。5人次。

  12. 第十四届全国免疫学学术大会，四川成都，2021年10月21-24日。2人次。

  13. 第八届医学图像计算青年研讨会，陕西西安，2021年7月10日。4人次。

  14. 空军军医大学军事航空医学论坛暨中华医学会航空航天医学持续发展论坛，北京，2021年9月22日，1人次。

五、获奖情况

  1. 第十三届全国生物力学学术会议，“大会优秀学术论文”，陈志浩，博士后。

  2. 中国抗癌协会肿瘤标志专业委员会，第二届非编码RNA与肿瘤前沿论坛，优秀墙报一等奖，2019，陈志浩，博士后。

  3. 美国骨矿物研究学会（ASBMR），美国骨矿物研究学会2019年年会（骨科国际top会议）青年学者旅行奖金，2019，陈志浩，博士后。

  4. 陕西省细胞生物学学会，陕西省细胞生物学学会2020年年会，“青年优秀论文”二等奖，2020，陈志浩，博士后。

  5. 中国力学学会中国生物医学工程学会生物力学专业委员会，第十三届全国生物力学学术会议，“大会优秀学术论文”，2021，陈志浩，博士后。

  6. 中国细胞生物学会细胞工程与转基因生物分会，中国细胞生物学会细胞工程与转基因生物分会第四届学术年会，“三类青年优秀论文”，2021，陈志浩，博士后。

  7. 中国细胞生物学学会2021年“百名优秀党员”，骞爱荣，教授。

  8. 2021年陕西高等学校科学技术特等奖（第八完成人），非编码RNA信号网络在肿瘤恶性行为调控中的作用及机制，温伟红，教授。

  9. 西北工业大学2020-2021年博士研究生一等学业奖学金，淮莹，博士。

  10. 西北工业大学2020-2021年硕士研究生一等学业奖学金，徐霞，硕士。

  11. 西北工业大学，2020-2021年中国国家奖学金，冯虎虎，硕士。

  12. 西北工业大学学术委员会，西北工业大学优秀博士论文，2022，陈志浩，博士后。

  13. 中国细胞生物学会细胞工程与转基因生物分会，中国细胞生物学会细胞工程与转基因生物分会第五届学术年会，“三类青年优秀论文”，2023，陈志浩，博士后。