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Job
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We are looking for people:

Postdocts: Previous research focused on the fields of cell biology, molecular biology and transgenic mouse.

If you are interested in this position ,please feel free to contact with prof.Airong Qian.

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Tel：+86-029-88461840

Email：qianair@nwpu.edu.cn

ADD：127 West Youyi Road,Xi'an Shaanxi，710072

Publications & Patents

一、Publications (*: Corresponding Author):

  1. Wenjuan Zhang#, Ying Huai#, Wei Wang, Kaiyue Xue, Lei Chen, Chu Chen*,Airong Qian*. A Retrospective Cohort Study on the RiskFactors of Deep Vein Thrombosis (DVT) for Traumatic Fracture Patients atHonghui Hospital. BMJ Open, 2018 Nov (accepted).

  2. WenjuanZhang, Ying Huai, Zhiping Miao, Chu Chen, Mohamed Shahen,Siddiq Ur Rahman, Mahmoud Alagawany, Mohamed E. Abd El-Hack*, Heping Zhao*,Airong Qian*. Systems pharmacology approach to investigate the molecularmechanisms of herb Rhodiola rosea L. radix. Drug Development IndustrialPharmacology, 2018 Nov 17:1-9.

  3. Peihong Su, Ye Tian, Chaofei Yang, Xiaoli Ma, Xue Wang, Jiawei Pei, and Airong Qian*.   Mesenchmal Stem Cell Migration during Bone Formation and Bone Diseases Therapy.Int. J. Mol. Sci.2018, 19(8), 2343; https://doi.org/10.3390/ijms19082343

  4. Yong-Guang Gao, Xiao Lin , Kai Dang, Shan-Feng Jiang, Ye Tian, Fen-Li Liu, Di-Jie Li, Yu Li, Zhi-Ping Miao and Ai-Rong Qian. Structure-activity relationship of novel low generation dendrimers for gene delivery. Organic & Biomolecular Chemistry, 2018, DOI: 10.1039/C8OB01767K

  5. Yong-Guang Gao, Uzair Alam, Ai-Xiang Ding, Quan Tang, Zheng-Li Tan, You-Di Shi, Zhong-Lin Lu, Ai-Rong Qian, [12]aneN3-based lipid with naphthalimide moiety for enhanced gene transfection efficiency. Bioorganic Chemistry, 2018, 79, 334-340.

  6. Hu L, Yin C, Zhao F, Ali A, Ma J, Qian A*. Mesenchymal StemCells: Cell Fate Decision to Osteoblast or Adipocyte and Application in Osteoporosis Treatment. Int J Mol Sci. 2018 Jan 25;19(2)

  7. Li S, Miao Z, Tian Y, Wang H, Wang S, He T, Yang Y, Wang P,Ma M, Yang T, Qian A* and Chen C*. Limethason reduces airway inflammation in a murine model ofovalbumin-induced chronic asthma without causing side effects. Experimental and Therapeutic Medicine. January 4, 2018

  8. Zhang Y, Yin C, Hu L, Chen Z, Zhao F, Li D, Ma J, Ma X, Su P,Qiu W, Yang C, Wang P, Li S, Zhang G, Wang L, Qian A*, Xian C. MACF1Overexpression by Transfecting the 21-kbp Large Plasmid PEGFP-C1A-ACF7 PromotesOsteoblast Differentiation and Bone Formation. Hum Gene Ther. 2018 Jan 15

  9. Yin C1,2,3, Zhang Y1,2,3, Hu L1,2,3, Tian Y1,2,3, Chen Z1,2,3, Li D1,2,3, Zhao F1,2,3, Su P1,2,3, MaX1,2, Zhang G2,3, Miao Z1,2,3, Wang L4, Qian A1,2,3, Xian CJ4. Mechanical unloading reducesmicrotubule actin crosslinking factor 1 expression to inhibit beta-cateninsignaling and osteoblast proliferation. J Cell Physiol. 2017 Dec 8.

  10. Qian A1,Hu L2. Spectraplakins, versatile roles in physiologyand pathology. Semin Cell Dev Biol. 2017 Sep; 69:1-2.

  11. Miao Z, Ali A, Hu L, Zhao F, Yin C, Chen C, Yang T, Qian A*. Microtubule actin cross-linking factor 1, a novel potential target in cancer. Cancer Sci. 2017 Oct;108(10):1953-8.

  12. Zhihao Chen, Yan Zhang, Chao Liang, Lei Chen, Ge Zhang* and Airong Qian*; Mechanosensitive miRNAs and Bone Formation. Int .J .Mol. Sci. 2017, 18(8), 1684.

  13. Ali A1, Hu L1, Zhao F1, Qiu W1, Wang P1, Ma X1, Zhang Y1, Chen L1, Qian A2.BPAG1, a distinctive role in skin and neurological diseases.Semin Cell Dev Biol. 2017 Jun 13.doi:10.1016/j.semcdb.2017.06.005

  14. Hu L1,2,3, Su P1,2,3, Yin C1,2,3, Zhang Y1,2,3, Li R1,2,3, Yan K1,2,3, Chen Z1,2,3, Li D1,2,3, Zhang G2,3, Wang L4, Miao Z1,2,3, Qian A1,2,3, Xian CJ4.Microtubule actin crosslinking factor 1 promotes osteoblast differentiation by promoting β-catenin/TCF1/Runx2 signaling axis.J Cell Physiol. 2017 Jun 16. doi: 10.1002/jcp.26059.

  15. Hu L1, Xiao Y1, Xiong Z1, Zhao F1, Yin C1, Zhang Y1, Su P1, Li D1, Chen Z1, Ma X1, Zhang G2, Qian A3. MACF1,versatility in tissue-specific function and in human disease.Semin Cell Dev Biol. 2017 May 31. pii: S1084-9521(16)30321-4.   doi: 10.1016/j.semcdb.2017.05.017.

  16. MIAO Zhi-ping,QIU Wu-xia,MA Xiao-li,QIAN Ai-rong. Advances in Ｒesearch on Effects of Space Microgravity on Bone Metabolism. Journal of Astronautics.DOI: 10.3873/j.issn.1000-1328.2017. 03.001

  17. Miao Zhiping,Yin Chong,Zhang Yan,Hu Li-fang,Li Dijie,Chen Zhihao,Qian Airong. Effects of Simulated Weightlessness with Ｒandom Positioning Machine on Microtubule Actin Crosslinking Factor 1 Expression and β-catenin Pathway in Osteoblast. Space Medicine ＆ Medical Engineering. 2017,30(1): 7-11

  18. Hu L1, Su P1, Li R1, Yin C1, Zhang Y1, Shang P1, Yang T2, Qian A1.Isoforms, structures, and functions of versatile spectraplakin MACF1.BMB Rep. 2016 Jan;49(1):37-44.   doi: 10.5483/BMBRep.2016.49.1.185.

  19. Kun Yan,Yasir Arfat,Dijie Li,Fan Zhao,Zhihao Chen,Chong Yin,Yulong Sun,Lifang Hu,Tuanmin Yang* & Airong Qian*.Structure Prediction:New Insights into Decrypting Long Noncoding RNAs. Int.J.Mol.Sci.2016,17(1),132 .

  20. Zhihao Chena, Fan Zhaoa, Yiduo Qia, Lifang Hua, Dijie Lia, Chong Yina, Peihong Sua, Yan Zhanga,

    Jianhua Maa,b, Jing Qiana, Hongpo Zhoua, Yiwei Zoua, Airong Qiana*, Simulated microgravity alters the expression of cytoskeleton- and ATP binding-related genes in MLO-Y4 osteocytes.Acta Astronautica 129 (2016) 186–192.

  21. Li Dijie1，Chen Zhihao1，Liu Zonglin1，Lin Yu1，Ding Chong1，Zhao Fan1，Arfat Yasir1，Hu Lifang1，Li Yongzhi2* ，Shang Peng1* ，Qian Airong1*.Qiang Gu Kang Wei Prescription Increases Bone Mineral Density of Load-bearing Bone in Tail Suspended Rats.Space Medicine & Medical Engineering.2016, 29(1)

  22. Lifang Hu, Peihong Su, Runzhi Li, Kun Yan, Zhihao Chen, Peng Shang & Airong Qian*. Knockdown of microtubule actin crosslinking factor 1 inhibits cell proliferation in MC3T3-E1 osteoblastic cells. BMB Rep. 2015, 48(10):583-8.

  23. Lifang Hu, Peihong Su, Runzhi Li, Chong Yin, Yan Zhang, Peng Shang, Tuanmin Yang& Airong Qian*. MACF1, a versatile spectraplakin: isoforms, unique structures, and functions. BMB Rep. 2015 Nov 2. pii: 3336.

  24. Yang Wang, ZhiHao Chen, Chun Yin, JianHua Ma, DiJie Li, Fan Zhao, YuLong Sun, LiFangHu, Peng Shang*, AiRong Qian*.GeneChip Expression Profiling Reveals the Alterations of Energy MetabolismRelated Genes in Osteocytes under Large Gradient High Magnetic Fields.PLoS One. 2015, 10 (1): e0116359.

  25. Yasir Arfat,WeiZhong Xiao, Munazza Ahmad, Fan Zhao, Di-Jie Li, Yu-Long Sun, Li-Fang Hu,ZhiHao Chen, Ge Zhang, Peng Shang, AiRong Qian*. Role of microRNAs in osteoblasts differentiation and bone disorders.Current Medicinal Chemistry. 2015, 22 (6):748-58.

  26. YuLong Sun, Xiao-Hu Chen, ZhiHao Chen, Xiao-Li Ma,DiJie Li, Peng Shang, AiRong Qian*.Neuropeptide FF attenuates RANKL-induced differentiation of RAW264.7 cells intoosteoclast-like cells. Archives of Oral Biology. 2015, 60,282-292.

  27. YuLong Sun, Zhi-Hao Chen, XiaoHu Chen, Chong Yin,DiJie Li, Xiao-Li Ma, Fan Zhao, Ge Zhang, Peng Shang*, AiRong Qian*. Diamagnetic levitation promotes osteoclast differentiation from RAW264.7 cells. IEEE Transactions on Biomedical Engineering.2015, 62(3): 900-8.

  28. Chao Liang, Baosheng Guo,Heng Wu, NingSheng Shao, DeFang Li, Jin Liu, Lei Dang, Cheng Wang, Hui Li,Shao-Hua Li, Wing Ki Lau, Yu Cao, ZhiJun Yang, Cheng Lu, XiaoJuan He, D W TAu, XiaoHua Pan, BaoTing Zhang, ChangWei Lu, HongQi Zhang, KinMan Yue, AiRong Qian, Peng Shang, JiaKe Xu,LianBo Xiao, ZhaoXiang Bian, WeiHong Tan, ZiCai Liang, FuChu He,LingQiang Zhang*, AiPing Lu* & Ge Zhang*. Aptamer-functionalized lipidnanoparticles targeting osteoblasts as a novel RNA interference-based boneanabolic strategy. Nature Medicine. 2015, 21(3): 288-94.

  29. Jin Liu, LeiDang, DeFang Li, Chao Liang, XiaoJuan He, Heng Wu, AiRong Qian, ZhiJun Yang, Au, Doris W.T. Chiang, Michael W.L.,BaoTing Zhang, QuanBin Han, Yue, Kevin K.M. ; HongQi Zhang, ChangWei Lv,XiaoHua Pan, JiaKe Xu, ZhaoXiang Bian, Peng Shang, WeiHong Tan, ZiCai Liang, BaoSheng Guo, AiPing Lu, Ge Zhang. A delivery system specifically approaching bone resorption surfaces to facilitate therapeutic modulation ofmicroRNAs in osteoclasts. Biomaterials. 2015, 52:148-160.

  30. Yasir Arfat, Nasir Mahmood, Muhammad Usman Tahir,Maryam Rashid,Sameer Anjum, Fan Zhao, DiJie Li, YuLong Sun, Li-fang Hu,Zhihao Chen, Chong Yin, Peng Shang, AiRongQian*. Effect of imidacloprid on hepatotoxicity and nephrotoxicityin malealbino mice. Toxicology Reports, 2014, 1:554–561

  31. Yasir Arfat*, Nasir Mahmood, Munazza Ahmad, Muhammad Tayyab, Fan Zhao, DiJie Li, ZhiHao Chen, Chong Yin, Peng Shang, AiRong Qian. Effect of date palmpollen on serum testosterone and intra-testicular environment in male albinorats. Journal of Pharmacy and Pharmacology, 2014, 8(31):793-800.

  32. Yasir Arfat,WeiZhong Xiao, Salman Iftikhar, Fan Zhao, DiJie Li, YuLong Sun, Ge Zhang,Peng Shang, AiRong Qian*.Physiological effects of microgravity on bone cells. Calcified Tissue Internationaland Musculoskeletal Research. 2014, 94: 569-579

  33. YuLong Sun,Zhi-Hao Chen, XiaoLi Ma, DiJie Li, Fan Zhao, Peng Shang, TuanMing Yang*, AiRong Qian*. NeuropeptideFF inhibits LPS-mediated osteoclast differentiation of RAW264.7 cells. Protein& Peptide Letters. 2014, 22 (3):270-84.

  34. LiFang Hu, RunZhi Li,PeiHong Su, Peng Shang, AiRong Qian*. Response and Adaptation of Bone Cells to Simulated Microgravity. Acta Astronautica.2014, 104 (1): 396-408.

  35. Fan Zhao, DiJie Li, Yasir Arfat, Zhihao Chen ,Zong-Lin Liu, Yu Lin, Chong Ding, YuLong Sun, LiFang Hu, Peng Shang. AiRong Qian*. Reloading partly recovers bone mineral density and mechanical properties in hind limb unloadedrats. Acta Astronautica. 2014,105 (1): 57-65.

  36. AiRong Qian, Xiang Gao, Wei Zhang, JingBao Li, Yang Wang,ShengMeng Di, LiFang Hu, Peng Shang* Large Gradient High Magnetic Fields Affect Osteoblast Ultrastructure and Function by Disrupting Collagen I orFibronectin / αβ1 Integrin.PLoS One. 2013, 8 (1): e51036.

  37. Ai-Rong Qian; DaChuan Yin, Peng-Fei Yang, Yi Lv, ZongChengTian, Peng Shang*. Application of diamagnetic levitation technology inbiological sciences research. IEEE Transactions on AppliedSuperconductivity, 2013, 23 (1): 3600305.

  38. AiRong Qian, Lei Wang, Xiang Gao, Wei Zhang, LiFang Hu, JingHan, JingBao Li, ShengMeng Di, Peng Shang*.Diamagnetic levitation causes changes in the morphology, cytoskeleton and focal adhesion proteins in osteocytes. IEEE Transactions on Biomedical Engineering. 2012, 59 (1): 68-77.

  39. AiRong Qian, DongLi, Jing Han, Xiang Gao, ShengMeng Di, Wei Zhang, LiFang Hu, Peng Shang*.Fractal dimension as a measure of altered actin cytoskeleton in MC3T3-E1 cells under simulated microgravity using 3-D/2-D clinostats. IEEE Transactions on Biomedical Engineering. 2012, 59 (5): 1374- 1380.

  40. AiRong Qian, J.-P. Jin*.H2-Calponin Dynamics and Function in Cytokinesis.Biophysical Journal.2012, 102 (3): 373a.

  41. AiRong Qian, PengFei Yang, LiFang Hu, Wei Zhang, ShengMeng Di, Zhe Wang, Xiang Gao,Li Xie, YinYin Weng, JianPin Cao, Peng Shang*. High magnetic gradient environment causes alterations of cytoskeleton and cytoskeleton associated genes in human osteoblasts cultured in vitro. Advances in Space Research, 2010,46: 687-700.

  42. ZongLin Liu, AiRongQian*, Peng Shang. MACF1 and cytoskeleton. Chinese Journal of Cellular andMolecular. 2012，28 (2): 209-211.

  43. Yu Lin, AiRong Qian*, ZongLin Liu, PengShang. A mice hindlimb unloading (HLU) model to simulate microgravity. SpaceMedicine & Medical Engineering. 2012, 25 (4): 239-242.

  44. Wang Yang, AiRong Qian*, Peng Shang. The roles of stanniocalcin in bone metabolism in mammal.Chinese Journal of Cell Biology. 2014(4):343-348.

  45. AiRong Qian, PengFei Yang, LiFang Hu, Wei Zhang, ShengMeng Di, Zhe Wang, Xiang Gao, Li Xie, YinYin Weng, JianPin Cao, Peng Shang*. High magnetic gradient environment causes alterations of cytoskeleton and cytoskeleton associated genes in human osteoblasts cultured in vitro.Advances in Space Research, 2010, 46: 687-700.

二、 Books：

  1. AirongQian. Antibody Fusion Protein , see Beifen Shen,Zhinan Chen, Minpei Liu ,Ed in Chief, Recombinant Antibodies, 2005,Scientific Press.

三、 Patents：

  1. Fang Ye, Jin Xie, Meifang He, Airong Qian, Honglong Chong. Cell positioning culture chip based on single cell capture and use and preparation method thereof. CN-106047706-B.

  2. Airong Qian, Lifang Hu, Pai Wang, Xiaoli Ma, Fan Zhao, Wuxia Qiu, Ru Zhang, Lei Chen, Chong Yin, Zhihao Chen, Peihong Su, Dijie Li, Yan Zhang, Chaofei Yang, Siyu Li. Construction method of MACF1 fixed-point transgenic mouse model. 201710672223.6

  3. Airong Qian,Lifang Hu,Wuxia Qiu,Xiaoli Ma,Fan Zhao,Ru Zhang,Pai Wang,Lei Chen，Chong Yin,Zhihao Chen,Peihong Su,Dijie Li,Yan Zhang,Siyu Li,Chaofei Yang.Construction and Application of Mice Model with MACF1 Conditional Knockout in Osteoblasts.201710280283.3

  4. Airong Qian,Chong Yin,Zhiping Miao,Yan Zhang,Lifang Hu,Zhihao Chen,Fan Zhao,Dijie Li,Jianhua Ma,Peihong Su,Xiaoli Ma,Wuxia Qiu,Chaofei Yang,Siyu Li,Pai Wang.Application of Lnc-DIF.201710036464.1

  5. Airong Qian,Lifang Hu,Jianhua Ma,Siyu Li,Fan Zhao,Zhihao Chen,Dijie Li, Chu Chen,Tuanmin Yang,Chong Yin,Peihong Su,Xiaoli Ma,Yan Zhang,Wuxia Qiu,Ru Zhang,Pai Wang,Chaofei Yang.Serum microRNA diagnostic markers and diagnostic kits for Aged osteoporosis fracture.CN106591487A

  6. Airong Qian,Xiaoli Ma,Lifang Hu,Fan Zhao,Ru Zhang,Wuxia Qiu,Pai Wang,Peihong Su,,Zhihao Chen,Dijie Li,Chong Yin,Zhiping Miao,Lei Chen. Construction and application of a conditional knockout mouse model of MACF1 gene in mesenchymal stem cells. 201710008830.2

  7. Airong Qian,Jianhua Ma,Fan Zhao,Zhihao Chen,Lifang Hu,Dijie Li,Chong Yin,Xiaoli Ma,Peihong Su. Application of Oligonucleotide Compounds Associated With microRNA in Senile Osteoporosis. 201610555353.7

  8. Airong Qian,Lifang Hu,Chong Yin,Fan Zhao,Zhihao Chen,Yan Zhang,Jianhua Ma,Peihong Su,Dijie Li,Wuxia Qiu,Xiaoli Ma,Pai Wang. Application of MACF1 Gene and Its Expression Product in Producing Drug for Osteoporosis Diagnosed and Treated. 201610530383.2

  9. Airong Qian,Lifang Hu,Chong Yin,Yan Zhang,Jianhua Ma,Fan Zhao,Zhihao Chen,Dijie Li,siyu Li,Xiaoli Ma,Wuxia Qiu,Chaofei Yang,Pai Wang,Peihong Su. Application of miR-489-3p in Producing Drug for Osteoporosis Diagnosed and Treated. CN106011264A

  10. Airong Qian,Zhihao Chen, Yasir Arfst,Chong Yin,Lifang Hu,Fan Zhao,Dijie Li,Ya Zhang,Ruizhi Li,Peihong Su,Xiaoli Ma,Wuxia Qiu.Mechanical sensitivity of miR - 138-5 p as drugtargets applied in the musculoskeletal system disease. Patent Number: CN105169411A;

  11. Airong Qian,Peng Shang,Lifang Hu,Ruizhi Li,Peihong Su,Chong Yin,Kun Yan,Zhihao Chen,Yiduo Qi,Yulong Sun.An effective inhibit mice MACF1 shRNA screeningand application of gene expression.Patent Number: CN104531700A;

  12. Zhinan Chen,Baocheng Huang,Peng Shang,Airong Qian,Ping Zhu.HAb18G/CD147, its antagonist and application. Patent Number:ZL01131735.3;

  13. Peng Shang,Dachuan Yin,Airong Qian,Chaohua Shi,Xiaoping Xue,Zengxiang Fu,Bin Jia,Zongcheng Tian,Xuchu Zheng,Wei Zhang.Experimental facility for space gravitational biologyin the high gradient magnetic field. Patent Number: 101188069；

  14. Peng Shang,JingbaoLi,Gang He,Liang Wang,Airong Qian.The method for determination of protein concentration in solution by using glutaraldehyde induced infrared fluorescence.Patent Number: CN101846625A；

  15. JingbaoLi,Peng Shang,Yanan Li，Airong Qian.The method and apparatus for filtering and counting   stained   cells.Patent Number: ZL 201120119330.4；

  16. JingbaoLi,Peng Shang,Meng Wang，Jia Wang，Yanan Li,Airong Qian.A method for evaluating cell wall off strength using cell wall removal reagent. Patent Number: ZL201210199358.2.

四、Meetings:

  1. Airong Qian*, Zhihao Chen, Yasir Arfat, Lifang Hu, Peng Shang, Ge Zhang. Mechanical unloading sensitive miR-138 targets MACF1 to regulate bone formation. 2015 American Society for Bone and Mineral Research (ASBMR), Seattle, USA, 2015, Oct. 9-12.

  2. Airong Qian*, Lifang Hu, Yulong Sun, Zhihao Chen, Yasir Arfat, Dijie Li, Chong Yin, Peihong Su, Runzhi Li, Kun Yan, Peng Shang, Ge Zhang. The Response of MACF1 to Simulated Microgravity and Its Noncoding RNAs in Regulating Osteogenesis. 6th China-Germany Workshop on Microgravity and Space Life Sciences Hangzhou, China. 2015.Sept.25-28

  3. Airong Qian*, Lifang Hu, Yulong Sun, Zhihao Chen, Yasir Arfat, Dijie Li, Chong Yin, Peihong Su, Runzhi Li, Kun Yan, Peng Shang, Ge Zhang. The role of MACF1 and its noncoding RNA in osteogenesis. The International Chinese Musculoskeletal Research Society (ICMRS) Conference and Xiangya Osteoporosis Forum, Changsha, China. 2015, April 9-11.

  4. AiRong Qian*, Li-Fang Hu, YuLong Sun, DiJie Li, Zhi-Hao Chen, Peng Shang, Ge Zhang. The role of MACF1 inmigration, proliferation and differentiation of Osteoblast and the screening ofthe natural antisense transcripts of MACF1. 2014 American Society for Boneand Mineral Research (ASBMR), Houston, USA. 2014, Sept. 12-15. (ISTP)

  5. AiRong Qian*, LiFang Hu, Yang Wang, Peng Shang. Response and Adaption of Bone Cells to Mechanical Stimulation. 2013 American Society for Bone and Mineral Research (ASBMR),Boltimore, USA. 2013, Oct. 4-7. (ISTP)

  6. AiRong Qian*, Xiang Gao, Wei Zhang, Lifang Hu, Peng Shang, JianPing Jin. Diamagneic levitation changes morphology,cytoskeleton architecture and h2-calponin expression in bone cells. BiophysicalSociety 55th Annual Meeting. Baltimore, Maryland,Mar5-9,2011.