Fundings

1. National Natural Science Foundation of China

1. Qian Airong，“The mechanism of mechanosensitive miR-138-5p inhibits bone formation via regulating MACF1”（31570940）；

2. Qian Airong，“the roles of MACF1 and its NATs in effect of simulated microgravity in migration preosteoblasts”（31370845）；

3. Qian Airong，“the mechanism of microtubule actin crosslinking factor (MACF1) involved in mechanotransduction of osteocyte”.（30970706）；

4. Qian Airong，“The interaction between microtubule-actin crosslinking factor (MACF1) and cytoskeleton in the process of osteoblast sensing gravity”.（30840030）；

5. Qian Airong，“the mechanism of matrix metalloproteinase production induced by Extracellular matrix metalloproteinase inducer”.(30300189）；

6. Li Yu, "Function and Mechanism of CD147 Regulating FOXM1 Ubiquitination Degradation Involved in DNA Damage Resistance of Ovarian Cancer Cisplatin-Resistant Cells" (81872129);

7. HuLifang，“The role of MACF1 in simulated weightlessnessinhibiting osteoblast differentiation through regulating Wnt/β-cateninsignaling”(31400725).

8. HuLifang，“The role and mechanism of MACF1 combined with CDK12 in simulating weightless inhibition of bone formation”(81772017);

9. Lin Xiao, "The mechanism of MACF1/TCF4/miR-335 axis in senile osteoporosis"(81700784);

10. Tian Ye, "MACF1 regulates the anti-oxidation of osteoblasts through the FOXO1/β-catenin pathway and participates in the mechanism of simulated weightless inhibition of bone formation" (81801871);

2. 863 Program

1. National Hightech Research and Development Program of China（863 Program, Key grant, No.2008AA12A220）.

2. National Hightech Research and Development Program of China（863 Program, Key grant, No.2008AA12A218）.

3.Program for New Century Excellent Talents in University of Ministry of Education of China

1. Qian Airong，“the mechanism of gravisensing of bone cells” (NCET-12-0469).

4. Natural Science Basic Research Program of Shaanxi

1. Qian Airong, "Natural Science Basic Research Program - Surface Project, Screening and Functional Verification of Microtubule Microfilament Crosslinking Molecular Natural Antisense Transcripts" (2015JM3078)

2. Qian Airong, "Shaanxi Key Research and Development Program - Key Project of International Science and Technology Cooperation Program, Biosynthesis Technology for Recombinant Functional Small RNA" (2018KWZ-10)

3. Hu Lifang, "The role and mechanism of MACF1 involved in simulating pre-osteoblast migration induced by weightlessness" (2015JQ3076)

4. Miao Zhiping, "Key Research and Development Program in Shaanxi Province: Development of Diagnostic Kit for Osteoporosis in Postmenopausal Women" (2018SF-263)

5. Qian Airong, "Shaanxi Province Innovation and Entrepreneurship Dual Tutor System Project: Research and Development of Diagnostic Kit for Senile Osteoporosis" (2018KA180038C180038)

6. Hu Lifang, Young Talent Fund of University Association for Science and Technology in Shaanxi,   "The role and mechanism of MACF1 in senile osteoporosis by binding to CDK12" (No. 20170401) 2018.1~2019.12

7. Tian Ye，“General Project of Natural Science Basic Research Program of Shaanxi Province (Youth): "The Mechanism of MACF1 Regulating MAP1B Participation in Bone Formation”（2018JQ8032)

8. Lin Xiao，“Shaanxi Natural Science Foundation Youth Project: "The Role of MACF1/TCF4/miR-335 in Osteogenic Differentiation of MSC"” (2018JQ3049).

5. China Postdoctoral Science Foundational

1. Hu Lifang，"Study on the role of MACF1-induced cytoskeletal rearrangement in weightlessness inhibiting bone formation" (No. 2017M610653), 2017.3~2018.12

2. Hu Lifang，“Studyon the role of MACF1 in simulated weightlessness inhibiting bone formation”(2014M562450)；

3. Hu Lifang，“Therole and mechanism of miR-138-5p in simulated weightlessness inhibiting boneformation”(2015T81051)，postdoctoral special funding.

4. LiXiao, "The regulation of MACF1/miR-335 in MSCs differetiation of osteoporosis"(2017M613196)

5. TianYe, "The role of MACF1 in simulated weightlessness-induced inhibition of osteoblast differentiation through regulating cellular redox balance "(No.2017M613210)

6. Zhang Wenjuan, "Discussion on the material basis and mechanism of action of Huang Qi's heart and brain treatment based on network pharmacology" (2017M623249)

6. Shaanxi Postdoctoral Project

1. Hu Lifang, "The role of MACF1 in regulating cytoskeletal rearrangement in the development of senile osteoporosis";

2. TianYe, "Biosynthesis of recombinant small RNA and its therapeutic effect on weight loss bone loss"

7. Shenzhen Science and Technology Plan Projects

1. Airong Qian,“The Role and Mechanism of MACF1-LncRNA in Senile Osteoporosis”.(JCYJ20160229174320053).

8. Basic Research Foundation of NPU

1. Qian Airong，“The biological effects and its mechanism of simulation gravitational environment on osteoblast”；

2. Qian Airong，“the mechanism of gravisensing of bone cells” (JC201055);

3. Hu Lifang，“Studyon the molecular mechanism of preosteoblast migration to bone formation surface”(3102014JKY15007).

4. Hu Lifang，“A Novel Non-coding RNA Regulates the Molecular Mechanism of MACF1 Involved in Bone Formation”(3102016ZY037).

5. TianYe, "Application of recombinant functional small RNA in the treatment of osteoporosis" (3102018zy053).

9. Other

1. Central University Basic Research Business Funding Project: Zhang Wenjuan, "The material basis and molecular mechanism of jaundice multi-target synergy" (31020170QD050);

2. Central University Basic Research Business Funding Project: Lin Xiao, "Correlation between natural antisense MACF1-AS and bone formation" (3102017QD041);